Furosemide, brand name Lasix
is a diuretic medication used to treat
heart failure, liver impairment, kidney
disease, and high blood pressure.
Furosemide inhibits the reabsorption of sodium and chloride
from the Loop of Henle and distal renal tubule and increases renal
excretion of water, sodium, chloride, magnesium, potassium, and
Furosemide diuresis and mobilizes excess fluid.
(Peripheral and pulmonary edema.)
Adverse Side Effects:
Erythema Multiforme, Steven Johnson's Syndrome,
Toxic Epidermal Necrolysis, Aplastic Anemia, and
Safety has not been established in pregnant or lactating women.
Elderly adults may have increased risk of side effects, especially
hypotension and electrolyte imbalance, at usual doses.
Steven Johnson's Syndrome
Drug to Drug Interactions
Increased risk of hypotension with antihypertensives, nitrates,
or acute ingestion of alcohol.
Increased risk of hypokalemia with other diuretics, amphotericin B,
stimulant laxatives and corticosteroids.
Hypokalemia may increase risk of digoxin toxicity and increase
risk of arrhythmia in patients taking drugs that prolong the QT
Decreased lithium excretion, may cause lithium toxicity.
Increase risk of ototoxicity with aminoglycoside or cisplatin.
Continued Drug to Drug Interactions:
Increase risk of nephrotoxicity with cisplatin.
NSAIDS decrease effects of furosemide.
May increase risk of methotrexate toxicity.
Decrease effects when given at the same time with sucralfate,
cholestyramine, or colestipol.
Increase risk of salicylate toxicity(with high dose salicylate therapy).
Concurrent use with cyclosporinemay increase risk of gouty arthritis.
Pertinent Information for Patient :
Take Furosemide as directed. Take missed dose as soon as possible and
don't double doses. Change positions slowly to minimize orthostatic
hypotension. Use caution with use of alcohol, exercise during hot
weather, or standing for long periods of time may enhance
orthostatic hypotension. Consult you HCP regarding a diet high in
potassium. Contact HCP for a weight gain of more than 3lbs. in 1 day.
Notify HCP of all OTC medications, vitamins, or herbal supplements
taken and consult with HCP before staring any new OTC medications.
Instruct HCP of medication regimen before any treatment or procedure.
Use sunscreen and protective clothing to prevent photosensitivity
Pertinent Information for Patients:
CONTACT HCP IMMEDIATELY IF RASH, MUSCLE WEAKNESS, CRAMPS
NAUSEA, DIZZINESS, NUMBNESS, OR TINGLING OF EXTREMETIES
Diabetic patients monitor blood glucose closely as treatment may
cause increased blood glucose levels. Notify HCP if pregnant or
planning to become pregnant, or if breast feeding. Monitor fetal
growth during pregnancy. Increased risk for higher birth weights.
Follow up exams are of the utmost importance.
Increased risk of falls in elderly.
Continue antihypertensive regimen even if feeling better. Furosemide
controls but does not cure hypertension. Reinforce continued additional
therapies for hypertension. Smoking cessation, weight loss, diet