Levothyroxine [Copy]

Levothyroxine [Copy]

Published on 27 November 2022
Transcript
00:02
Levothyroxine
00:07
Levothyroxine
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Trade names:  Synthroid Levoxyl Unithyroid Tirosint
00:14
Generic name: Levothyroxine (T4)
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Uses: To treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone To treat enlarged thyroid glands, also called goiter To treat thyroid cancer
00:47
How it works
00:49
Levothyroxine increases the body's metabolic rate, which increases: oxygen consumption respiratory rate heart rate
00:59
*Absorption of the drug varies from 48-79% after taking
01:04
Therapeutic Effects
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When evaluating for therapeutic effects, conditions that should be considered are: increased energy level of alertness and interest in surroundings increased blood pressure and pulse rate bowel movement regularity/reduced constipation healthy skin and hair
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Side Effects
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Most Common: decreased bone density fatigue weight loss hair loss insomnia joint pain skin rash
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vomiting or diarrhea headache fever leg cramps changes in appetite heat sensitivity
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Most Severe: atrial fibrillation fast or weak pulse disorientation sudden headache loss of coordination loss of consciousness heart attack heart failure
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Dosage Range (adults and children 12 yrs and older)
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Oral capsules: 1.7mcg/kg  Oral solution: starting dose is 1.7mcg/kg, adjusted as needed Oral tablet: 1.6mcg/kg
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*Dosage varies by form and use, these dosage ranges focus on treatment of hypothyroidism
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Drug Interactions
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Medications that interfere with the absorption of Levothyroxine: antacids ferrous sulfate (iron supplement) calcium carbonate Lanthanum Cholestyramine Colesevelam
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*These medications can still be used while taking levothyroxine, just separate administration times by 4-6 hours
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Patient Teaching
02:18
Thyroid hormone is required for normal body function. When the thyroid gland is unable to produce enough thyroid hormone, levothyroxine is a synthetic substitute.
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Dosage adjustments may occur over time based on clinical response and results of thyroid function tests.
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For best results, Levothyroxine should be taken first thing in the morning, 30 minutes before breakfast.
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Take Levothyroxine at the same time every day for more consistent body metabolism.
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Learning Assessment Questions:
02:46
What condition is treated with Levothyroxine?
02:49
What lab value tests for Levothyroxine levels?