SACUHART VA V.1

SACUHART VA V.1

Published on 11 February 2023
Transcript
00:00
Dear Doctor, Don’t let their hearts fail Promise to secure them
00:07
Dear Doctor, Introducing, In HFrEF SACUHART, the brand of Sacubitril+Valsartan available in 50/100 mg Tablets. Doctor, promise to secure the failing heart Doctor, SACUHART is recommended in HFrEF as a replacement for ACEi/ARB 1.Improves breathlessness 2.Reduces the risk of hHF 3.Improves Survival
00:35
Dear Doctor, Neprilysin & RAAS both are elevated in HF & are predictive of CV death and hHF Sacubitrilat, the active form of Sacubitril, inhibits Neprilysin and enhances Vasorelaxation. Valsartan blocks binding of Angiotensinogen II to AT1 receptor and inhibits vasoconstrictions. Also Guidelines (ACC/AHA/HFSA 2022 & ESC 2021) recommend ARNI as the first line of treatment in HFrEF instead of ACEi
01:15
Dear Doctor, Support their spirit to live As SACUHART improves HF parameters Decreases NT-ProBNP upto 73% in De Novo HF patients & upto 40% in ACEi treated patients Increases LVEF upto 14% Improves NYHA class by decreasing the proportion of NYHA Class III-IV patients from 44.6%-24%