Teaching resource, lantus Molly Weaver [Copy] [Copy]

Transcript

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Long acting insulin: Lantus insulin glargine [rDNA origin] injection

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MollyWeaver

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small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration time profile over 24 hours with no peak  this makes it a patient’s basal insulin comes in subq injection or orally.

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Pharmacodynamics

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After subcutaneous injection of insulin glargine in healthy subjects and in patients with diabetes, the insulin serum concentrations indicated a slower, more prolonged absorption and a relatively constant concentration/time profile over 24 hours

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Pharmacokinetics

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Uses

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improve glycemic control in patients with type 1 diabetes mellitus

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Improve glycemic control in patients with type 2 diabetes mellitus 

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Special Implications

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Contraindicated during episodes of hypoglycemia or diabetic ketoacidosis. drug interactions with ACE inhibitors, Beta-blockers Discourage drinking alcohol

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Possible adverse reactions 

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allergic reactions to the diluent site injection reactions or infection lipodystrophy at the injection site Hypoglycemia know what signs and symptoms 

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help keep blood sugar within normal ranges

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Therapeutic effects expected

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Question 1) what is lantus used to treat?

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Question2) True or False, patient should continue to drink alcohol?